Down syndrome

Down syndrome
Down syndrome

There are so much news about celebrities getting married and giving birth to their adorable children nowadays. But giving birth to a strong and healthy baby is not an easy thing to be achieved. During the nine months of pregnancy she has to be very careful of anything that may be harmful to her child, including diseases. One of the most significant genetic disorders is ‘Down Syndrome. Down Syndrome is a genetic disorder from an extra pair of chromosome. The approximate number of children being born with Down syndrome in Thailand is 1 per 1,000. One of the most important risk factors is the age of the mother. The older the mother the more chances for their children to have Down syndrome.

The general conditions that can be found in the patients with Down syndrome are: Abnormality in body structures such as a flat face, small and disfigured ears, small lips, pointed up eyes, small white dots at the iris, a big tongue, and short and separated fingers and being shorter than normal. Slow brain development, causing the person to have a low IQ Abnormality in the functionality of their organs; such as valvular heart disease, gastrointestinal tract, thyroid hormone disorders and low immunity. In general, we would have 23 pairs of a chromosome or 46 chromosomes (23 from the father and 23 from the mother). People with Down syndrome have 47 chromosomes.

Down  syndrome may be divided into three main types: Trisomy 21 is the extra chromosome in chromosome 21 from an abnormality in the mother’s egg cell division. This is the most common disorder 94 percent. Translocation is where a part of chromosome 21 moves or switches with another pair of chromosomes (mostly chromosome 14). This type of Down syndrome has 4 percent chance of occurring. Mosaicism is where there are two types of cell; a situation in which different cells in the same individual have different numbers or arrangements of chromosomes. This type of Down syndrome has fewer symptoms as there are still functioning normal cells. It also has the least chance of occurring with a 2 percent chance only. Down syndrome is a genetic disorder that cannot be prevented and cannot be cured. A doctor’s consultation during pregnancy can evaluate risk factors through ultrasound, amniocentesis and blood examination.

Provided by Healthlab Hua Hin